The p75 neurotrophin receptor has nonapoptotic antineurotrophic actions in the basal forebrain.

@article{Greferath2012ThePN,
  title={The p75 neurotrophin receptor has nonapoptotic antineurotrophic actions in the basal forebrain.},
  author={Ursula Greferath and Jennifer Trieu and Graham L. Barrett},
  journal={Journal of neuroscience research},
  year={2012},
  volume={90 1},
  pages={
          278-87
        }
}
Because of controversy about the role of the p75 neurotrophin receptor (p75(NTR) ) in the cholinergic basal forebrain (CBF), we investigated this region in p75(NTR) third exon knockout mice that were congenic with 129/Sv controls. They express a shortened intracellular form of p75(NTR) , permitting detection of p75(NTR) -expressing cells. We performed separate counts of choline acetyltransferase (ChAT)-expressing and p75(NTR) -expressing neurons. In agreement with past reports, the number of… CONTINUE READING
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