The p66shc gene expression in peripheral blood monocytes is increased in patients with coronary artery disease.

@article{Noda2010ThePG,
  title={The p66shc gene expression in peripheral blood monocytes is increased in patients with coronary artery disease.},
  author={Yoshihiro Noda and Sho-ichi Yamagishi and Takanori Matsui and So Ueda and Shin-ichiro Ueda and Yuko Jinnouchi and Yuji Hirai and Tsutomu Imaizumi},
  journal={Clinical cardiology},
  year={2010},
  volume={33 9},
  pages={548-52}
}
BACKGROUND The p66(shc) protein has been shown to control cellular responses to oxidative stress, being involved in atherosclerosis in animal models. However, the relationship between the p66(shc) gene expression levels and coronary artery disease (CAD) in humans remains unknown. In this study, we examined whether the p66(shc) gene expression in peripheral blood monocytes (PBMs) was increased in patients with CAD, compared with age- and sex-matched subjects without CAD. HYPOTHESIS We… CONTINUE READING
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