The p38 kinases MKK4 and MKK6 suppress metastatic colonization in human ovarian carcinoma.

@article{Hickson2006ThePK,
  title={The p38 kinases MKK4 and MKK6 suppress metastatic colonization in human ovarian carcinoma.},
  author={Jonathan A. Hickson and Dezheng Huo and Donald J. Vander Griend and Anning Lin and Carrie W. Rinker-Schaeffer and Seiko Diane Yamada},
  journal={Cancer research},
  year={2006},
  volume={66 4},
  pages={2264-70}
}
Despite considerable efforts to improve early detection of ovarian cancer, the majority of women at time of diagnosis will have metastatic disease. Understanding and targeting the molecular underpinnings of metastasis continues to be the principal challenge in the clinical management of ovarian cancer. Whereas the multistep process of metastasis development… CONTINUE READING