The p38 and ERK MAP kinase pathways cooperate to activate Ternary Complex Factors and c-fos transcription in response to UV light.

Abstract

We investigated the activation of c-fos transcription following UV irradiation, a 'stress' stimulus. In both HeLa TK- and NIH 3T3 cells the Serum Response Element is required for efficient UV-induced c-fos transcription, and in HeLa TK- cells the Ternary Complex Factor (TCF) binding site contributes substantially to activation. Consistent with this, UV… (More)

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Cite this paper

@article{Price1996ThePA, title={The p38 and ERK MAP kinase pathways cooperate to activate Ternary Complex Factors and c-fos transcription in response to UV light.}, author={M. A. Price and Francisco H. Cruzalegui and Ruth A Treisman}, journal={The EMBO journal}, year={1996}, volume={15 23}, pages={6552-63} }