The p130 isoform of angiomotin is required for Yap-mediated hepatic epithelial cell proliferation and tumorigenesis.

Abstract

The Hippo-Yap signaling pathway regulates a number of developmental and adult cellular processes, including cell fate determination, tissue growth, and tumorigenesis. Members of the scaffold protein angiomotin (Amot) family interact with several Hippo pathway components, including Yap (Yes-associated protein), and either stimulate or inhibit Yap activity… (More)
DOI: 10.1126/scisignal.2004060

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Cite this paper

@article{Yi2013ThePI, title={The p130 isoform of angiomotin is required for Yap-mediated hepatic epithelial cell proliferation and tumorigenesis.}, author={Chunling Yi and Zhewei Shen and Anat Stemmer-Rachamimov and Noor B. Dawany and Scott A. Troutman and Louise C. Showe and Qin Liu and Akihiko Shimono and Marius Sudol and Lars Holmgren and Ben Z. Stanger and Joseph L Kissil}, journal={Science signaling}, year={2013}, volume={6 291}, pages={ra77} }