The oxidative damage of butenolide to isolated erythrocyte membranes.

@article{Wang2007TheOD,
  title={The oxidative damage of butenolide to isolated erythrocyte membranes.},
  author={Yi-Mei Wang and Shuang-qing Peng and Qi Zhou and Min-wei Wang and Chang-Hui Yan and Guo-qiang Wang and Hai-ying Yang},
  journal={Toxicology in vitro : an international journal published in association with BIBRA},
  year={2007},
  volume={21 5},
  pages={863-9}
}
Butenolide (CAS No. 16275-44-8), a mycotoxin produced by several Fusarium species, has been shown to be a potential risk factor for animal and human health. This study was undertaken to investigate the potential oxidative damage of butenolide to biomembranes in vitro using the erythrocyte membrane model. Following exposure of isolated rat erythrocyte membranes to butenolide, the extent of oxidative damage was assessed by measuring lipid peroxidation, -SH groups content, Ca2+/Mg2+-ATPase and Na… CONTINUE READING