The ovarian progestogen receptor in the spotted seatrout, Cynoscion nebulosus, demonstrates steroid specificity different from progesterone receptors in other vertebrates.

@article{Pinter1997TheOP,
  title={The ovarian progestogen receptor in the spotted seatrout, Cynoscion nebulosus, demonstrates steroid specificity different from progesterone receptors in other vertebrates.},
  author={Joseph Pinter and Philippe Thomas},
  journal={The Journal of steroid biochemistry and molecular biology},
  year={1997},
  volume={60 1-2},
  pages={113-9}
}
A nuclear progestogen receptor has previously been characterized in the ovary of the spotted seatrout. The steroid specificity of this receptor was further defined in the present study by determining the binding affinity of a wide variety of progestin and corticosteroid agonists and antagonists. The addition of a hydroxyl or keto group to the 11 position resulted in a 10-100-fold decrease in relative binding affinity (RBA). The significance of the 17, 20, and 21 positions in determining the RBA… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

Similar Papers

Loading similar papers…