The osmZ (bglY) gene encodes the DNA-binding protein H-NS (H1a), a component of the Escherichia coli K12 nucleoid

@article{May1990TheO,
  title={The osmZ (bglY) gene encodes the DNA-binding protein H-NS (H1a), a component of the Escherichia coli K12 nucleoid},
  author={Gerhard May and Petra Dersch and Martin Haardt and Anke Middendorf and Erhard Bremer},
  journal={Molecular and General Genetics MGG},
  year={1990},
  volume={224},
  pages={81-90}
}
A class of trans-acting mutations, which alter the osmoregulated expression of the Escherichia coli proU operon, maps at 27 min on the chromosome in a locus we have called osmZ. Mutations in osmZ are allelic to bglY, pilG and virR, affect gene expression, increase the frequency of the site-specific DNA inversion mediating fimbrial phase variation, stimulate the formation of deletions, and influence in vivo supercoiling of reporter plasmids. We have cloned the osmZ + gene, mapped it at 1307 kb… CONTINUE READING

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