The orphan receptor GPR55 is a novel cannabinoid receptor.

  title={The orphan receptor GPR55 is a novel cannabinoid receptor.},
  author={Erik Ryberg and Niklas H P Larsson and Sven Sj{\"o}gren and Stephan Hjorth and N-O Hermansson and J. Y. Leonova and Thomas Elebring and Karolina Nilsson and Tomas Drmota and Peter J Greasley},
  journal={British journal of pharmacology},
  volume={152 7},
BACKGROUND The endocannabinoid system functions through two well characterized receptor systems, the CB1 and CB2 receptors. Work by a number of groups in recent years has provided evidence that the system is more complicated and additional receptor types should exist to explain ligand activity in a number of physiological processes. EXPERIMENTAL APPROACH Cells transfected with the human cDNA for GPR55 were tested for their ability to bind and to mediate GTPgammaS binding by cannabinoid… CONTINUE READING
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