The origins of the Drosophila leg revealed by the cis-regulatory architecture of the Distalless gene.


Limb development requires the elaboration of a proximodistal (PD) axis, which forms orthogonally to previously defined dorsoventral (DV) and anteroposterior (AP) axes. In arthropods, the PD axis of the adult leg is subdivided into two broad domains, a proximal coxopodite and a distal telopodite. We show that the progressive subdivision of the PD axis into… (More)
DOI: 10.1242/dev.029975


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