The origins and uses of mouse outbred stocks

  title={The origins and uses of mouse outbred stocks},
  author={Ruth Chia and Francesca Achilli and Michael Fw Festing and Elizabeth M. C. Fisher},
  journal={Nature Genetics},
Outbred mouse stocks, often used in genetics, toxicology and pharmacology research, have been generated in rather haphazard ways. Understanding the characteristics of these stocks and their advantages and disadvantages is important for experimental design. In many studies these mice are used inappropriately, wasting animals' lives and resources on suboptimal experiments. Recently, however, researchers from the field of complex trait analysis have capitalized on the genetics of outbred stocks to… CONTINUE READING
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Contributions to Behaviour-Genetic Analysis: The Mouse as a Prototype 3–22 (Appleton Centry

  • G. E. McClearn, J. R. Wilson, W. Meredith
  • 2005

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