The origin of the diversity of crotoxin isoforms in the venom of Crotalus durissus terrificus.

@article{Faure1994TheOO,
  title={The origin of the diversity of crotoxin isoforms in the venom of Crotalus durissus terrificus.},
  author={Grazyna Faure and Val{\'e}rie Choumet and Christiane Bouchier and Luc Camoin and Jeanette L Guillaume and B Mon{\'e}gier and Marc Vuilhorgne and Cassian Bon},
  journal={European journal of biochemistry},
  year={1994},
  volume={223 1},
  pages={161-4}
}
Crotoxin, the main toxin from the venom of the South American rattlesnake Crotalus durissus terrificus, is a beta-neurotoxin which consists of the non-covalent association of two subunits: a phospholipase A2 subunit B (CB), and a non-enzymic subunit A (CA). We have previously purified and characterized several isoforms of each subunit of crotoxin in the venom collected from numerous snakes. Furthermore, three cDNAs encoding two CB isoforms and the precursor, pro-CA, of subunit A have been… CONTINUE READING
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