The origin of the acidosis in hyperlactataemia.

  • Joan F Zilva
  • Published 1978 in Annals of clinical biochemistry


Anaerobic glycolysis produces lactate, ATP, and water but there is no net change in the number of hydrogen ions: it does not produce lactic acid. The acidosis usually associated with hyperlactataemia is caused by hydrolysis of the ATP, with release of hydrogen ions. By contrast, ATP turnover by aerobic mechanisms is not acidifying because the released… (More)


Cite this paper

@article{Zilva1978TheOO, title={The origin of the acidosis in hyperlactataemia.}, author={Joan F Zilva}, journal={Annals of clinical biochemistry}, year={1978}, volume={15 1}, pages={40-3} }