The origin of ovarian carcinomas: a unifying hypothesis.

@article{Auersperg2011TheOO,
  title={The origin of ovarian carcinomas: a unifying hypothesis.},
  author={Nelly Auersperg},
  journal={International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists},
  year={2011},
  volume={30 1},
  pages={
          12-21
        }
}
It is currently a controversial issue whether epithelial ovarian cancers arise in the ovarian surface epithelium (OSE) or the fimbrial epithelium of the oviduct. The hypothesis presented here aims to reconcile these 2 views and provides a possible explanation for 2 questions arising: first, why tumors originating in the fimbriae and OSE, which are parts of different organs, express common features; second, why these epithelia are prone to neoplastic transformation whereas the remaining oviduct… CONTINUE READING
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