The origin of human fecal alkaline phosphatase


Fecal alkaline phosphatase activity may derive from biliary secretions, desquamated intestinal epithelial cells, and/or colonic flora. The data presented demonstrate the mimetic nature of fecal activity with that of jejunal mucosal biopsy specimens in respect to specific activity, Michaelis-Menten constants,l-phenylalanine inhibition, and electrophoretic mobility on polyacrylamide gel. We conclude that fecal alkaline phosphatase activity is predominately derived from small bowel.

DOI: 10.1007/BF01073014

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@article{Horrigan1974TheOO, title={The origin of human fecal alkaline phosphatase}, author={Francis D. Horrigan and Stuart H. Danovitch}, journal={The American Journal of Digestive Diseases}, year={1974}, volume={19}, pages={603-608} }