The origin of human cancers

@article{Cairns1981TheOO,
  title={The origin of human cancers},
  author={John Cairns},
  journal={Nature},
  year={1981},
  volume={289},
  pages={353-357}
}
The limited evidence available suggests that most human cancers are not caused by conventional mutagens but are more likely to be the result of genetic transpositions. Although the molecular biology of transposition is starting to be understood, the external factors that influence its frequency have not yet been studied in any detail. 

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