The origin and the clinical significance of urinary angiotensinogen in proteinuric IgA nephropathy patients.

@article{Jang2012TheOA,
  title={The origin and the clinical significance of urinary angiotensinogen in proteinuric IgA nephropathy patients.},
  author={Hye Ryoun Jang and Soo Min Kim and Yu-ji Lee and Jung Eun Lee and Wooseong Huh and Dae Joong Kim and Ha Oh and Y G Kim},
  journal={Annals of medicine},
  year={2012},
  volume={44 5},
  pages={448-57}
}
BACKGROUND Urinary angiotensinogen (AGT) was reported as a marker of renal injury in chronic kidney disease patients. However, the main source of urinary AGT is unknown in proteinuric patients because the disrupted filtration barrier might cause AGT filtration. We investigated the origin and the clinical importance of urinary AGT in proteinuric IgA nephropathy (IgAN) patients. METHODS In patients with biopsy-proven IgAN, urinary and plasma AGT was measured using a sandwich ELISA and compared… CONTINUE READING

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