The origin and development of glial cells in peripheral nerves

  title={The origin and development of glial cells in peripheral nerves},
  author={K. Jessen and R. Mirsky},
  journal={Nature Reviews Neuroscience},
  • K. Jessen, R. Mirsky
  • Published 2005
  • Biology, Medicine
  • Nature Reviews Neuroscience
  • During the development of peripheral nerves, neural crest cells generate myelinating and non-myelinating glial cells in a process that parallels gliogenesis from the germinal layers of the CNS. Unlike central gliogenesis, neural crest development involves a protracted embryonic phase devoted to the generation of, first, the Schwann cell precursor and then the immature Schwann cell, a cell whose fate as a myelinating or non-myelinating cell has yet to be determined. Embryonic nerves therefore… CONTINUE READING
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