The origin and development of glial cells in peripheral nerves

@article{Jessen2005TheOA,
  title={The origin and development of glial cells in peripheral nerves},
  author={Kristjan R Jessen and Rhona Mirsky},
  journal={Nature Reviews Neuroscience},
  year={2005},
  volume={6},
  pages={671-682}
}
During the development of peripheral nerves, neural crest cells generate myelinating and non-myelinating glial cells in a process that parallels gliogenesis from the germinal layers of the CNS. Unlike central gliogenesis, neural crest development involves a protracted embryonic phase devoted to the generation of, first, the Schwann cell precursor and then the immature Schwann cell, a cell whose fate as a myelinating or non-myelinating cell has yet to be determined. Embryonic nerves therefore… Expand
View on Nature
ncbi.nlm.nih.gov
1,116 Citations
Highly Influential Citations
118
Background Citations
543
Methods Citations
28
Results Citations
11

1,116 Citations

Citation Type

Citation Type

Neural Crest Cell Diversification and Specification: ErbB Role
TLDR
Signaling of a neuronal growth factor to glial receptor tyrosine kinases of the ErbB family has emerged as a central regulator of SC development and several aspects of myelination, including regulation of the ensheathment fate, myelin thickness, and remyelination after nerve injury. Expand
Signaling pathways that regulate glial development and early migration—Schwann cells
TLDR
The Schwann cell lineage is understood in general outline and the embryonic phase of the lineage is described, including the radial sorting that leads to the generation of promyelin cells in 1:1 relationships with axons around birth. Expand
Development of the Schwann cell lineage: From the neural crest to the myelinated nerve
TLDR
The biology of the transitional stages in embryonic and early postnatal Schwann cell development, including the phenotypic differences between them and the recently identified signaling pathways, are discussed and the role and importance of the microenvironment in which glial differentiation takes place will be discussed. Expand
Schwann Cells: Development and Role in Nerve Repair.
TLDR
The signals that control the embryonic phase of this process and the organogenesis of peripheral nerves are described and the phenotypic plasticity retained by mature Schwann cells is discussed. Expand
New insights on schwann cell development
TLDR
Both seminal discoveries and recent advances in understanding of the molecular mechanisms that drive Schwann cell development and myelination are discussed, with a focus on cell–cell and cell–matrix signaling events. Expand
Specification, plasticity and evolutionary origin of peripheral glial cells
TLDR
The major features of the Schwann cell lineage are reviewed and an evolutionary discussion around possible relations between central and peripheral glial cells is discussed. Expand
Nerve-associated neural crest: peripheral glial cells generate multiple fates in the body.
TLDR
This review outlines the field and focuses on the capacity of nerve-associated glial progenitors to contribute to the development and regeneration of numerous tissues in various groups of vertebrates. Expand
Schwann cell development
TLDR
Methods of discriminating between the various lineage stages and some of the signals that influence their development, including sex-determining region Y box 10 (SOX10), neuregulin, and Notch, are discussed, and the novel origin of Schwann cells in spinal roots is described. Expand
Neuronal lineages derived from the nerve-associated Schwann cell precursors
TLDR
The genesis of Schwann cell precursors is discussed, their role in building peripheral neural structures and the role in the origin in congenial diseases associated with peripheral nervous systems are pondered. Expand
Axo-glial interdependence in peripheral nerve development
TLDR
This Review focuses on the specific interdependence of axons and Schwann cells in peripheral nerve development that enables axonal outgrowth, Schwann cell lineage progression, radial sorting and, finally, formation and maintenance of the myelin sheath. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 136 REFERENCES
The Early Life of a Schwann Cell
TLDR
The aim of this review is to summarize the molecular and cellular characteristics of the first steps in the life of a Schwann cell, the development from a multipotent neural crest cell to a differentiated Schwann Cell. Expand
Schwann cells and their precursors emerge as major regulators of nerve development
TLDR
The evidence indicates that glial-derived signals are necessary for neuronal survival at crucial periods of development, that they regulate the molecular and functional specialization of axons and that they control the maturation of the perineurial sheath that protects nerves from inflammation and unwanted macro-molecules produced in the surrounding tissues. Expand
The schwann cell precursor and its fate: A study of cell death and differentiation during gliogenesis in rat embryonic nerves
TLDR
Evidence that the survival of Schwann cell precursors is regulated by neurons is provided and basic fibroblast growth factor is identified as a potential key regulator of apoptosis in Schwann Cell precursor and of precursor to Schwanncell conversion are identified. Expand
Mechanisms of axon ensheathment and myelin growth
TLDR
This review highlights four crucial stages of myelination, namely, the selection of axons and initiation of cell–cell interactions between them and glial cells, the establishment of stable intercellular contact and assembly of the nodes of Ranvier, regulation of myelin thickness and longitudinal extension ofMyelin segments in response to the lengthening of axONS during postnatal growth. Expand
Cell death in the Schwann cell lineage and its regulation by neuregulin.
TLDR
It is found that Schwann cells isolated from postnatal day 3 rat sciatic nerve undergo apoptosis in vitro upon serum withdrawal and that SchwANN cell death can be prevented by beta forms of neuregulin (NRG-beta) but not by fibroblast growth factor 2 or platelet-derived growth factors AA and BB. Expand
The glial identity of neural stem cells
  • F. Doetsch
  • Biology, Medicine
  • Nature Neuroscience
  • 2003
TLDR
Differentiation along the glial lineage may be a default state of development reflected in the progression of stem cells along the neuroepithelial→radial glia→astrocyte lineage. Expand
Glial cells.
  • K. Jessen
  • Medicine
  • The international journal of biochemistry & cell biology
  • 2004
TLDR
Increasing body of evidence indicates that glial cells are essential regulators of the formation, maintenance and function of synapses, the key functional unit of the nervous system. Expand
Schwann cell development in embryonic mouse nerves
TLDR
In the mouse, the transition from precursors to Schwann cells takes place 2 days earlier than in the rat, and is accompanied by the appearance of the O4 antigen and the establishment of an autocrine survival circuit. Expand
Radial Glial Cells Defined and MajorIntermediates between EmbryonicStem Cells and CNS Neurons
TLDR
Evidence for the distinct "glial" nature of radial glial cells is reviewed and progenitors with clear glial antigenic characteristics act as cellular intermediates are contrasted with the neuroepithelial cells. Expand
Neural crest boundary cap cells constitute a source of neuronal and glial cells of the PNS
TLDR
Data indicate that BC cells constitute a source of peripheral nervous system (PNS) components that, after the major neural crest ventrolateral migratory stream, feeds a secondary wave of migration to the PNS. Expand
...
1
2
3
4
5
...