The origin and development of glial cells in peripheral nerves

@article{Jessen2005TheOA,
  title={The origin and development of glial cells in peripheral nerves},
  author={Kristjan R Jessen and Rhona Mirsky},
  journal={Nature Reviews Neuroscience},
  year={2005},
  volume={6},
  pages={671-682}
}
Key PointsThe Schwann cell precursor (SCP) represents the first step in the process of gliogenesis in growing nerves. In addition to generating Schwann cells, these cells are likely to provide essential trophic support to sensory and motor neurons and are necessary for the structural cohesion of peripheral nerves. They also have the potential to generate neurons and may be the source of the fibroblast population that is found in peripheral nerves.In many ways our ideas about CNS and PNS glial… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 134 REFERENCES

Analysis of congenital hypomyelinating Egr2Lo/Lo nerves identifies Sox2 as an inhibitor of Schwann cell differentiation and myelination

N Le
  • Proc. Natl Acad. Sci. USA 102,
  • 2005

Coordinate control of axon defasciculation and myelination by laminin-2 and -8

D Yang
  • J. Cell Biol
  • 2005

Defined and major intermediates between embryonic stem cells and CNS neurons

M. Gotz, Barde, Y.-A
  • Neuron 46,
  • 2005

Neuroglia 2nd edn

K. R. Jessen, R. Mirsky
  • 2005

Peripheral Neuropathy

R. Mirsky, K. R. Jessen
  • 2005