The optimization of porous polymeric scaffolds for chondrocyte/atelocollagen based tissue-engineered cartilage.

@article{Tanaka2010TheOO,
  title={The optimization of porous polymeric scaffolds for chondrocyte/atelocollagen based tissue-engineered cartilage.},
  author={Yoko Tanaka and Hisayo Yamaoka and Satoru Nishizawa and Satoru Nagata and Toru Ogasawara and Yukiyo Asawa and Yuko Fujihara and Tsuyoshi Takato and Kazuto Hoshi},
  journal={Biomaterials},
  year={2010},
  volume={31 16},
  pages={4506-16}
}
To broaden the clinical application of cartilage regenerative medicine, we should develop an implant-type tissue-engineered cartilage with firmness and 3-D structure. For that, we attempted to use a porous biodegradable polymer scaffold in the combination with atelocollagen hydrogel, and optimized the structure and composition of porous scaffold. We administered chondrocytes/atelocollagen mixture into the scaffolds with various kinds of porosities (80-95%) and pore sizes (0.3-2.0 mm… CONTINUE READING

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The application of atelocollagen gel in combination with porous scaffolds for cartilage tissue engineering and its suitable conditions

YamaokaH, Y Tanaka, +3 authors K Hoshi
J BiomedMater Res A 2009;93:123e32 • 2009
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