The optimal concentration of topical hydroxycamptothecin in preventing intraarticular scar adhesion

Abstract

10-Hydroxycamptothecin could reduce intraarticular adhesion by inhibiting fibroblasts proliferation after knee surgery. However, the ideal concentration of hydroxycamptothecin have not been defined. This study was tried to verify the optimal concentration of 10-hydroxycamptothecin in preventing knee intraarticular adhesion. Sixty rabbits were randomly… (More)
DOI: 10.1038/srep04621

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