The optimal analysis of MRI data to quantify the distribution of a microbicide.

@article{Barnhart2006TheOA,
  title={The optimal analysis of MRI data to quantify the distribution of a microbicide.},
  author={Kurt Thomas Barnhart and Elmari Pretorius and David Shera and Mayadah Shabbout and Alka Shaunik},
  journal={Contraception},
  year={2006},
  volume={73 1},
  pages={82-7}
}
OBJECTIVE The objective of this study was to systematically review the use of MRI for the evaluation of deployment characteristics of vaginal microbicides and to understand the relationship of gel spread with potential influencing factors. METHODS Data from four clinical trials that used MRI to assess the deployment of a vaginal gel were combined. A linear mixed model best represented the spread of gel over time. Significant covariates that influence vaginal gel spread are baseline dimensions… CONTINUE READING

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Division of the vagina into two distinct anatomical regions best explains difference in gel spread , i.e. , upper area ( above the pelvic diaphragm ) and lower area ( below pelvic diaphragm ) .
Division of the vagina into two distinct anatomical regions best explains difference in gel spread , i.e. , upper area ( above the pelvic diaphragm ) and lower area ( below pelvic diaphragm ) .
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