The ontogeny of adhesion molecules expressed on the vascular endothelium of the developing human skin.

@article{Davies1996TheOO,
  title={The ontogeny of adhesion molecules expressed on the vascular endothelium of the developing human skin.},
  author={Joanna Davies and Mary Dyson and Yildiz Mustafa and Frances Compton and Mary Perry},
  journal={Journal of anatomy},
  year={1996},
  volume={189 ( Pt 2)},
  pages={373-82}
}
One of the important functions of adhesion molecules is to regulate the trafficking of lymphocytes and other leucocytes between the different organs and tissues of the body. These molecules are expressed on both the endothelial cells and the leucocytes, enabling them to adhere to one another and ultimately lead to extravasation of the leucocytes from the circulation into the surrounding tissue. P and E-selectin promote 'rolling' of leucocytes along the blood vessel walls, whereas ICAM-1 and… CONTINUE READING

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