The ontogeny, structure and function of the human T lymphocyte receptor for antigen and major histocompatibility complex.

@article{Reinherz1986TheOS,
  title={The ontogeny, structure and function of the human T lymphocyte receptor for antigen and major histocompatibility complex.},
  author={Ellis L. Reinherz and Hans Dieter Royer and Thomas J. Campen and Dunia Ramarli and Marina Fabbi and Oreste Acuto},
  journal={Biochemical Society symposium},
  year={1986},
  volume={51},
  pages={211-32}
}
Recent studies using cloned antigen-specific T lymphocytes and monoclonal antibodies directed at their various surface glycoprotein components have led to identification of the human T cell antigen receptor as a surface complex comprised of a clonotypic 90 kDa Ti heterodimer and the invariant 20 and 25 kDa T3 molecules. Approximately 30,000-40,000 Ti and T3… CONTINUE READING