The only function of Grauzone required for Drosophila oocyte meiosis is transcriptional activation of the cortex gene.

@article{Harms2000TheOF,
  title={The only function of Grauzone required for Drosophila oocyte meiosis is transcriptional activation of the cortex gene.},
  author={Emily Harms and T Chu and G Henrion and Steve Strickland},
  journal={Genetics},
  year={2000},
  volume={155 4},
  pages={1831-9}
}
The grauzone and cortex genes are required for the completion of meiosis in Drosophila oocytes. The grauzone gene encodes a C2H2-type zinc-finger transcription factor that binds to the cortex promoter and is necessary for high-level activation of cortex transcription. Here we define the region of the cortex promoter to which Grauzone binds and show that the binding occurs through the C-terminal, zinc-finger-rich region of the protein. Mutations in two out of the five grauzone alleles result in… CONTINUE READING

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