The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas.

@article{Ligon2004TheOL,
  title={The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas.},
  author={Keith L Ligon and John A. Alberta and Alvin T. Kho and Jennifer Weiss and Mary R. Kwaan and Catherine L. Nutt and David N Louis and Charles D. Stiles and David H Rowitch},
  journal={Journal of neuropathology and experimental neurology},
  year={2004},
  volume={63 5},
  pages={
          499-509
        }
}
Astrocytomas, oligodendrogliomas, and oligoastrocytomas, collectively referred to as diffuse gliomas, are the most common primary brain tumors. These tumors are classified by histologic similarity to differentiated astrocytes and oligodendrocytes, but this approach has major limitations in guiding modern treatment and research. Lineage markers represent a potentially useful adjunct to morphologic classification. The murine bHLH transcription factors Olig1 and Olig2 are expressed in neural… CONTINUE READING

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Oligodendrocyte lineage genes (OLIG) as molecular markers for human glial brain tumors.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2001
VIEW 4 EXCERPTS