The oestrogenized rat myometrium inhibits organotypic sympathetic reinnervation.

  title={The oestrogenized rat myometrium inhibits organotypic sympathetic reinnervation.},
  author={M. M{\'o}nica Brauer and Rebeca Ch{\'a}vez-Genaro and Anal{\'i}a Richeri and Lorena Viettro and {\'A}lvaro Fr{\'i}as and Geoffrey Burnstock and Timothy Cowen},
  journal={Autonomic neuroscience : basic & clinical},
  volume={101 1-2},
Chronic administration of oestrogen to rats during the infantile/prepubertal period provokes, at 28 days of age, complete loss of noradrenaline-labelled intrauterine sympathetic nerves. It is not known whether oestrogen inhibits the growth or causes the degeneration of developing uterine sympathetic nerves, or whether the uterus recovers its innervation following cessation of infantile/prepubertal oestrogen treatment. In the present study, we analysed the time-course of the effects of oestrogen… CONTINUE READING


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