The odontogenic differentiation of human dental pulp stem cells on nanofibrous poly(L-lactic acid) scaffolds in vitro and in vivo.

@article{Wang2010TheOD,
  title={The odontogenic differentiation of human dental pulp stem cells on nanofibrous poly(L-lactic acid) scaffolds in vitro and in vivo.},
  author={Jing Wang and Xiaohua Liu and Xiaobing Jin and Haiyun Ma and Jiang Lei Hu and Longxing Ni and Peter X Ma},
  journal={Acta biomaterialia},
  year={2010},
  volume={6 10},
  pages={
          3856-63
        }
}
The aim of this study was to investigate the odontogenic differentiation of human dental pulp stem cells (DPSCs) on nanofibrous (NF)-poly(l-lactic acid) (PLLA) scaffolds in vitro and in vivo. Highly porous NF-PLLA scaffolds which mimic the architecture of collagen type I fibers were fabricated by the combination of a phase-separation technique and a porogen-leaching method. The human DPSCs were then seeded onto the scaffolds and cultured in different media for odontogenic differentiation… CONTINUE READING
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