The odds of immunotherapy success

@article{Gubin2015TheOO,
  title={The odds of immunotherapy success},
  author={Matthew M Gubin and Robert D. Schreiber},
  journal={Science},
  year={2015},
  volume={350},
  pages={158 - 159}
}
Mutation load correlates with the response of melanomas to immunotherapy [Also see Report by Van Allen et al.] Cancer immunotherapy has advanced to the forefront of molecular medicine as a consequence of the success of monoclonal antibodies (mAbs) that block immune checkpoints. Such antibodies, like ipilimumab, reverse cancer-induced immunosuppression and induce durable therapeutic responses in certain cancer patients (1). However, because only some patients respond to checkpoint blockade… 
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