The odd-skipped family of zinc finger genes promotes Drosophila leg segmentation.

@article{Hao2003TheOF,
  title={The odd-skipped family of zinc finger genes promotes Drosophila leg segmentation.},
  author={Irene Hao and Ryan B. Green and Olga Dunaevsky and Judith A. Lengyel and Cordelia Rauskolb},
  journal={Developmental biology},
  year={2003},
  volume={263 2},
  pages={282-95}
}
Notch signaling controls formation of joints at leg segment borders and growth of the developing Drosophila leg. Here, we identify the odd-skipped gene family as a key group of genes that function downstream of the Notch receptor to promote morphological changes associated with joint formation during leg development. odd, sob, drm, and bowl are expressed in a segmental pattern in the developing leg, and their expression is regulated by Notch signaling. Ectopic expression of odd, sob, or drm can… CONTINUE READING