The occurrence of Raynaud's phenomenon in a general population: the Framingham Study.

@article{Brand1997TheOO,
  title={The occurrence of Raynaud's phenomenon in a general population: the Framingham Study.},
  author={Frances Brand and Martin G. Larson and William Bernard Kannel and J. M. McGuirk},
  journal={Vascular medicine},
  year={1997},
  volume={2 4},
  pages={296-301}
}
The prevalence and predisposing conditions for primary and secondary Raynaud's phenomenon (RP) were examined in The Framingham Study based on 16 years of follow-up of a cohort of 4182 men and women. The association with atypical chest pain and migraine headache was also investigated. Over the 16 years of follow-up there were 130 men and 171 women who developed primary RP. The prevalence in women (9.6%) was somewhat higher than in men (8.1%) and 81.4% of the RP was primary. Secondary RP was… CONTINUE READING
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