The occurrence of C-H...O hydrogen bonds in proteins.

  title={The occurrence of C-H...O hydrogen bonds in proteins.},
  author={Zygmunt Derewenda and Lisa Lee and Urszula Derewenda},
  journal={Journal of molecular biology},
  volume={252 2},
Hydrogen bonds are a major feature of protein structure. By a generally accepted definition, they occur whenever a proton is shared by two electronegative atoms. Hence, only hydrogens bonded to nitrogen and oxygen atoms are usually considered in analyses of protein hydrogen bond networks. However, X-ray and neutron diffraction studies have shown that crystals of various organic compounds exhibit close C-H...X contacts (where X is an electronegative atom, in most cases oxygen) which show all the… CONTINUE READING


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