The obligatory role of the kidney in long-term arterial blood pressure control: extending Guyton's model of the circulation.


We describe a model for the essential role of the kidney in long-term blood pressure regulation. We begin with a simple hydraulic model for the circulation, with a constant circulating volume. We show, with the help of a modification of Guyton's classic diagram, that cardiac output and mean arterial pressure are functions of circulating volume, peripheral… (More)
DOI: 10.1111/j.1365-2044.2009.06052.x


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