The objective severity assessment of atopic dermatitis score: an objective measure using permeability barrier function and stratum corneum hydration with computer-assisted estimates for extent of disease.

@article{Sugarman2003TheOS,
  title={The objective severity assessment of atopic dermatitis score: an objective measure using permeability barrier function and stratum corneum hydration with computer-assisted estimates for extent of disease.},
  author={Jeffrey L. Sugarman and Joachim Wilhelm Fluhr and Ashley J Fowler and Thomas Bruckner and T. L. Diepgen and Mary Lou Williams},
  journal={Archives of dermatology},
  year={2003},
  volume={139 11},
  pages={1417-22}
}
OBJECTIVES Clinical scores used to assess the severity of atopic dermatitis (AD) rely entirely on subjective criteria to evaluate the severity of lesions and the extent of involvement. The aim of this study was to develop an objective measure of AD severity by measuring stratum corneum (SC) functions and by using computer-assisted estimates of involved body surface areas (BSAs). DESIGN Barrier function of the SC was assessed by measuring transepidermal water loss, and SC hydration was… CONTINUE READING

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Comparison of different activity parameters in atopic dermatitis: correlation with clinical scores

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