The nutritional regulation of T lymphocyte function.

@article{Horrobin1979TheNR,
  title={The nutritional regulation of T lymphocyte function.},
  author={David F. Horrobin and MeharS. Manku and Michiko Oka and Reginald O Morgan and Stephen C. Cunnane and Afshan Ally and T. Ghayur and Mark W Schweitzer and RashidaA. Karmali},
  journal={Medical hypotheses},
  year={1979},
  volume={5 9},
  pages={
          969-85
        }
}

• David F. Horrobin, MeharS. Manku, +6 authors RashidaA. Karmali
• Published 1979 in Medical hypotheses

Prostaglandin (PG) E1 plays a major role in the regulation of thymus development and T lymphocyte function and the evidence for this is reviewed. The production of PGE1 is dependent on nutritional factors with linoleic acid, gamma-linolenic acid, pyridoxine, zinc and vitamin C playing key roles. Inadequate intake of any one of these will lead to inadequate PGE1 formation and defective T lymphocyte function. Megadoses of any one are likely to be only minimally effective in the absence of… CONTINUE READING

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