The number of tumor infiltrating T-cell subsets in lymph nodes from patients with Hodgkin lymphoma is associated with the outcome after first line ABVD therapy.

@article{Alonsolvarez2017TheNO,
  title={The number of tumor infiltrating T-cell subsets in lymph nodes from patients with Hodgkin lymphoma is associated with the outcome after first line ABVD therapy.},
  author={Sara Alonso-{\'A}lvarez and Mar{\'i}a Bel{\'e}n Vidriales and Mar{\'i}a Dolores Caballero and {\'O}scar Blanco and Noem{\'i} Puig and Alejandro Mart{\'i}n and Mar{\'i}a Jes{\'u}s Pe{\~n}arrubia and Esther Zato and Josefina Galende and Abelardo B{\'a}rez and Miguel Alcoceba and Alberto Orfao and Marcos Gonzalez and Ram{\'o}n Garc{\'i}a-Sanz},
  journal={Leukemia & lymphoma},
  year={2017},
  volume={58 5},
  pages={
          1144-1152
        }
}
Prognostic factors in Hodgkin lymphoma (HL) still fail to accurately identify high-risk patients. Tumor microenvironment in HL is a current focus of research for risk definition but few studies have focused on infiltrating lymphocytes. Here, we analyzed the number of tumor infiltrating lymphocytes by flow cytometry in diagnostic biopsies from 96 HL homogeneously treated patients with ABVD with or without radiotherapy. Most lymph node cells were lymphocytes (90 ± 17), with a median T/B/NK… CONTINUE READING