The number of intratumoral dendritic cells and zeta-chain expression in T cells as prognostic and survival biomarkers in patients with oral carcinoma.

@article{Reichert2001TheNO,
  title={The number of intratumoral dendritic cells and zeta-chain expression in T cells as prognostic and survival biomarkers in patients with oral carcinoma.},
  author={Torsten Eugen Reichert and Claudia Scheuer and Roger Day and Wilfried Wagner and Theresa L Whiteside},
  journal={Cancer},
  year={2001},
  volume={91 11},
  pages={
          2136-47
        }
}
BACKGROUND Dendritic cells (DCs) are antigen-presenting cells with a unique ability to cross prime T cells and generate strong antitumor responses. This study evaluates the presence and prognostic significance of DCs as well as functional T cells, which accumulate in the microenvironment in patients with oral squamous cell carcinoma (OSCC). METHODS Immunohistochemistry for S-100 positive or p55 positive DCs and for T-cell receptor (TcR)-associated zeta-chain expression in tumor-infiltrating… CONTINUE READING
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