The number of glutamate transporter subtype molecules at glutamatergic synapses: chemical and stereological quantification in young adult rat brain.

@article{Lehre1998TheNO,
  title={The number of glutamate transporter subtype molecules at glutamatergic synapses: chemical and stereological quantification in young adult rat brain.},
  author={Knut Petter Lehre and Niels Christian Danbolt},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1998},
  volume={18 21},
  pages={8751-7}
}
The role of transporters in shaping the glutamate concentration in the extracellular space after synaptic release is controversial because of their slow cycling and because diffusion alone gives a rapid removal. The transporter densities have been measured electrophysiologically, but these data are from immature brains and do not give precise information on the concentrations of the individual transporter subtypes. Here we show by quantitative immunoblotting that the numbers of the astroglial… CONTINUE READING
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