The nuisance of nuisance regression: Spectral misspecification in a common approach to resting-state fMRI preprocessing reintroduces noise and obscures functional connectivity

Abstract

Recent resting-state functional connectivity fMRI (RS-fcMRI) research has demonstrated that head motion during fMRI acquisition systematically influences connectivity estimates despite bandpass filtering and nuisance regression, which are intended to reduce such nuisance variability. We provide evidence that the effects of head motion and other nuisance… (More)
DOI: 10.1016/j.neuroimage.2013.05.116

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Cite this paper

@article{Hallquist2013TheNO, title={The nuisance of nuisance regression: Spectral misspecification in a common approach to resting-state fMRI preprocessing reintroduces noise and obscures functional connectivity}, author={Michael N. Hallquist and Kai Hwang and Beatriz Luna}, journal={NeuroImage}, year={2013}, volume={82}, pages={208-25} }