The nucleus raphe interpositus in spinocerebellar ataxia type 3 (Machado-Joseph disease).

  title={The nucleus raphe interpositus in spinocerebellar ataxia type 3 (Machado-Joseph disease).},
  author={Udo R{\"u}b and Ewout R. P. Brunt and Kristin Gierga and Christian Schultz and Henry L. Paulson and Rob de Vos and Heiko Braak},
  journal={Journal of chemical neuroanatomy},
  volume={25 2},
The nucleus raphe interpositus (RIP) plays an important role in the premotor network for saccades. Its omnipause neurons gate the activity of the burst neurons for vertical saccades lying within the rostral interstitial nucleus of the medial longitudinal fascicle and that for horizontal saccades residing in the caudal subnucleus of the pontine reticular formation. In the present study we investigated the RIP in five patients with clinically diagnosed and genetically confirmed spinocerebellar… CONTINUE READING
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