The nucleoskeleton: artefact, passive framework or active site?

@article{Cook1988TheNA,
  title={The nucleoskeleton: artefact, passive framework or active site?},
  author={Peter R. Cook},
  journal={Journal of cell science},
  year={1988},
  volume={90 ( Pt 1)},
  pages={1-6}
}
The quotations above are taken from E. B. Wilson's classic review of cell biology written in 1892-1893 and revised during the first quarter of this century (Wilson, 1928). Then, as now, many observers felt that a nucleoskeleton must organize the complicated contortions of the chromatin in the nucleus. What Wilson pointed out, however, still remains the central problem in the field are the different preparations of the nucleoskeleton that have been isolated, or seen microscopically, any more… CONTINUE READING