The nuclear receptor transcription factor, retinoid-related orphan receptor β, regulates retinal progenitor proliferation

@article{Chow1998TheNR,
  title={The nuclear receptor transcription factor, retinoid-related orphan receptor β, regulates retinal progenitor proliferation},
  author={Lely Chow and Edward M. Levine and Thomas A. Reh},
  journal={Mechanisms of Development},
  year={1998},
  volume={77},
  pages={149-164}
}
We examined the role of retinoid-related orphan receptor (ROR)beta, a member of the nuclear receptor family of transcription factors, in retinal neurogenesis. In situ hybridization studies showed that RORbeta is expressed in retinal progenitor cells in the embryonic rat retina. Further studies demonstrated that RORbeta colocalizes with Chx10, a transcription factor thought to influence retinal progenitor proliferation (Burmeister, M., Novak, J., Liang, M-Y., Basu, S., Ploder, L., Hawes, N.L… CONTINUE READING