The nuclear pore complex has entered the atomic age.

  title={The nuclear pore complex has entered the atomic age.},
  author={Stephen G. Brohawn and James R. Partridge and James R.R. Whittle and Thomas U Schwartz},
  volume={17 9},
Nuclear pore complexes (NPCs) perforate the nuclear envelope and represent the exclusive passageway into and out of the nucleus of the eukaryotic cell. Apart from their essential transport function, components of the NPC have important, direct roles in nuclear organization and in gene regulation. Because of its central role in cell biology, it is of considerable interest to determine the NPC structure at atomic resolution. The complexity of these large, 40-60 MDa protein assemblies has for… CONTINUE READING
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Components of coated vesicles and nuclear pore complexes share a common molecular architecture

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