The nuclear bile acid receptor FXR controls the liver derived tumor suppressor histidine-rich glycoprotein.

Abstract

The nuclear bile acid receptor Farnesoid X receptor (FXR) is strongly expressed in liver and intestine, controls bile acid and lipid homeostasis and exerts tumor-protective functions in liver and intestine. Histidine-rich glycoprotein (HRG) is an abundant plasma protein produced by the liver with the proposed function as a pattern recognition molecule… (More)
DOI: 10.1002/ijc.29312

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