The nuclear LIM domain interactor NLI mediates homo- and heterodimerization of LIM domain transcription factors.

@article{Jurata1998TheNL,
  title={The nuclear LIM domain interactor NLI mediates homo- and heterodimerization of LIM domain transcription factors.},
  author={Linda W. Jurata and Samuel L Pfaff and Gordon N. Gill},
  journal={The Journal of biological chemistry},
  year={1998},
  volume={273 6},
  pages={3152-7}
}
LIM domain-containing transcription factors are required for embryonic survival and for the determination of many cell types. The combinatorial expression of the LIM homeodomain proteins Isl1, Isl2, Lhx1, and Lhx3 in subsets of developing motor neurons correlates with the future organization of these neurons into motor columns with distinct innervation targets, implying a functional role for LIM homeodomain protein combinations in the specification of neuronal identity. NLI is a widely… CONTINUE READING

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