The nuclear DNA content of human breast carcinoma. Associations with clinical stage, axillary lymph node status, estrogen receptor status and outcome.

@article{Berryman1987TheND,
  title={The nuclear DNA content of human breast carcinoma. Associations with clinical stage, axillary lymph node status, estrogen receptor status and outcome.},
  author={Ian Berryman and Jennet M. Harvey and Gregory F. Sterrett and John M. Papadimitriou},
  journal={Analytical and quantitative cytology and histology},
  year={1987},
  volume={9 5},
  pages={429-34}
}
Using Feulgen-DNA cytophotometry, the nuclear DNA content was determined in specimens from 169 female patients with unilateral primary carcinoma of the breast. The tumors were classified as either diploid (73 cases: 43%) or hyperdiploid (96 cases), according to the ploidy of the tumor cells. Statistically significant associations were found between the DNA content and other characteristics of the patients and their tumors. (1) In postmenopausal women, inoperable tumors were more likely to be… CONTINUE READING