The novel vasoactive hormone, adrenomedullin, inhibits water drinking in the rat.

@article{Murphy1995TheNV,
  title={The novel vasoactive hormone, adrenomedullin, inhibits water drinking in the rat.},
  author={Tonya C. Murphy and Willis K Samson},
  journal={Endocrinology},
  year={1995},
  volume={136 6},
  pages={2459-63}
}
The novel hormone, adrenomedullin (AdM), which exerts potent hypotensive effects in the periphery and natriuretic actions in the kidney, was found to be antidipsogenic. Cerebroventricular injection of AdM (22, 44, and 88 pmol) resulted in a dose-related diminution of water drinking in response to subsequent central administration of 100 pmol angiotensin II. Additionally, 88 pmol AdM significantly inhibited the drinking response to overnight water deprivation and hyperosmotic challenge. No… CONTINUE READING

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