The novel progestin drospirenone and its natural counterpart progesterone: biochemical profile and antiandrogenic potential.

@article{Fuhrmann1996TheNP,
  title={The novel progestin drospirenone and its natural counterpart progesterone: biochemical profile and antiandrogenic potential.},
  author={U. Fuhrmann and R. Krattenmacher and E. Slater and K. Fritzemeier},
  journal={Contraception},
  year={1996},
  volume={54 4},
  pages={
          243-51
        }
}
  • U. Fuhrmann, R. Krattenmacher, +1 author K. Fritzemeier
  • Published 1996
  • Biology, Medicine
  • Contraception
    • Drospirenone is a novel progestin under clinical development that is similar to the natural hormone progesterone, combining potent progestogenic with antimineralocorticoid and antiandrogenic activities. This specific pharmacological profile of drospirenone is defined by its pattern of binding affinities to a variety of steroid hormone receptors. In the present study the affinity of drospirenone to the progesterone receptor (PR), the androgen receptor (AR), the glucocorticoid receptor (GR), the… CONTINUE READING
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