The novel progestin drospirenone and its natural counterpart progesterone: biochemical profile and antiandrogenic potential.

@article{Fuhrmann1996TheNP,
  title={The novel progestin drospirenone and its natural counterpart progesterone: biochemical profile and antiandrogenic potential.},
  author={U. Fuhrmann and R. Krattenmacher and E. Slater and K. Fritzemeier},
  journal={Contraception},
  year={1996},
  volume={54 4},
  pages={
          243-51
        }
}
  • U. Fuhrmann, R. Krattenmacher, +1 author K. Fritzemeier
  • Published 1996
  • Biology, Medicine
  • Contraception
  • Drospirenone is a novel progestin under clinical development that is similar to the natural hormone progesterone, combining potent progestogenic with antimineralocorticoid and antiandrogenic activities. This specific pharmacological profile of drospirenone is defined by its pattern of binding affinities to a variety of steroid hormone receptors. In the present study the affinity of drospirenone to the progesterone receptor (PR), the androgen receptor (AR), the glucocorticoid receptor (GR), the… CONTINUE READING
    180 Citations
    Drospirenone and its antialdosterone properties
    • 20
    The use of newer progestins for contraception.
    • 113
    Molecular mechanisms of steroid receptor-mediated actions by synthetic progestins used in HRT and contraception
    • 170
    • Highly Influenced

    References

    SHOWING 1-10 OF 16 REFERENCES
    Progestogens with antimineralocorticoid activity.
    • 61