The novel ependymin related gene UCC1 is highly expressed in colorectal tumor cells.

@article{Nimmrich2001TheNE,
  title={The novel ependymin related gene UCC1 is highly expressed in colorectal tumor cells.},
  author={Inko Nimmrich and Silke Erdmann and U Melchers and Slava Chtarbova and U. Finke and Sebastian Hentsch and Ingrid Hoffmann and Michael Oertel and Werner Hoffmann and Oliver M{\"u}ller},
  journal={Cancer letters},
  year={2001},
  volume={165 1},
  pages={71-9}
}
Normal cells differ from malignant tumor cells in the transcription levels of many different genes. Two colorectal tumor cell lines were compared with a normal colorectal cell line by differential display reverse transcription PCR to screen for tumor cell specific differentially transcribed genes. By this strategy the upregulation of a novel gene was detected designated as 'upregulated in colorectal cancer gene-1' (UCC1). The UCC1 gene transcript level is increased in cultured tumor cells and… CONTINUE READING