The novel antimicrobial peptide beta3-defensin is produced by the amnion: a possible role of the fetal membranes in innate immunity of the amniotic cavity.

@article{Buhimschi2004TheNA,
  title={The novel antimicrobial peptide beta3-defensin is produced by the amnion: a possible role of the fetal membranes in innate immunity of the amniotic cavity.},
  author={Irina Alexandra Buhimschi and Maher Jabr and Catalin Sorin Buhimschi and Anelia P Petkova and Carl P. Weiner and Ghassan M. Saed},
  journal={American journal of obstetrics and gynecology},
  year={2004},
  volume={191 5},
  pages={1678-87}
}
BACKGROUND Innate immunity evolved to eliminate microorganisms before, or after their entry into the tissues, but before enough antigen is available to activate an adaptive, immune response. Innate immunity is so successful that the majority of encountered microbes are neutralized. The beta-defensins are antimicrobial peptides produced by skin and mucosal surfaces and are an integral part of the innate immune system. The ability of the amnion cells, which are epithelial derivatives, to produce… CONTINUE READING