The normal cellular prion protein is strongly expressed by myeloid dendritic cells.

@article{Burthem2001TheNC,
  title={The normal cellular prion protein is strongly expressed by myeloid dendritic cells.},
  author={John Burthem and Britta Christina Urban and Anindita Pain and David J Roberts},
  journal={Blood},
  year={2001},
  volume={98 13},
  pages={3733-8}
}
Abnormal isoforms of the prion protein (PrP(Sc)) that cause prion diseases are propagated and spread within the body by "carrier" cell(s). Cells of the immune system have been strongly implicated in this process. In particular, PrP(Sc) is known to accumulate on follicular dendritic cells (FDCs) in individuals affected by variant Creutzfeld-Jakob disease. However, FDCs do not migrate widely and the natural history of prion disorders suggests other cells may be required for the transport of PrP… CONTINUE READING
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